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Chicago - Logan Square

2367 N Milwaukee Ave
Chicago, IL 60647
708-722-1488

Adult-Use & Medical

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Chicago - Midway

5650 S Archer Ave
Chicago, IL 60638
872-267-7038

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Chicago - River North

216 W Ohio St
Chicago, IL 60654
708-722-1009

Adult-Use Only

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Chicago - Tinley Park

16200 S Harlem Ave
Tinley Park, IL 60477
312-535-5720

Adult-Use & Medical

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Chicago Ridge

9820 S. Ridgeland Ave
Chicago Ridge, IL 60415
872-250-3890

Adult-Use & Medical

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Collinsville

1014 Eastport Plaza Dr
Collinsville, IL 62234
312-535-3905

Adult-Use & Medical

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Fairview Heights

114 Commerce Ln
Fairview Heights, IL 62208
217-492-8030

Adult-Use Only

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Northlake

39 W North Avenue
Northlake, IL 60164
708-786-4317

Adult-Use & Medical

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Springfield - Downtown

628 E. Adams St
Springfield, IL 62701
217-679-3283

Adult-Use & Medical

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Springfield - Horizon Dr

3201 Horizon Dr
Springfield, IL 62703
217-492-8182

Adult-Use & Medical

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Aberdeen

226 S. Philadelphia
Aberdeen, MD 21001
410-306-6099

Adult-Use & Medical

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Crofton

1657 Crofton Blvd
Crofton, MD 21114
410-264-1411

Adult-Use & Medical

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Ellicott City

10169 Baltimore National Pike
Ellicott City, MD 21402
410-988-6004

Adult-Use & Medical

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Laurel

14703 Baltimore Avenue, Suite B
Laurel, MD 20707
240-360-2616

Adult-Use & Medical

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Boston

272 Friend St
Boston, MA 02114
617-859-6411

Adult-Use Only, Delivery starting at 8:00 AM.

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New Bedford

95 Coggeshall St
New Bedford, MA 02746
508-418-6836

Adult-Use Only, Delivery starting at 8:30AM.

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Newton

1089 Washington St
Newton, MA 02465
617-655-6415

Adult-Use Only, Delivery starting at 8:00AM.

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Battle Creek

6010 B Dr N
Battle Creek, MI 49014
269-234-2807

Adult-Use Only

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Detroit

24363 Grand River Ave
Detroit, MI 48219
313-426-0521

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East Lansing

1415 Michigan Ave
East Lansing, MI 48823
517-803-4300

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Grand Rapids - 28th Street

2741 28th St., SE
Grand Rapids, MI 49512
616-330-3621

Adult-Use & Medical

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Grand Rapids - Century Ave

503 Century Ave SW
Grand Rapids, MI 49503
616-600-6870

Adult-Use Only

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Grand Rapids - Scribner Ave

1336 Scribner Ave., NW
Grand Rapids, MI 49504
616-330-5501

Adult-Use Only

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Morenci

1096 E Main St.
Morenci, MI 49256
517-458-3002

Adult-Use Only

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East Coasting

Eatontown

178 Highway 35
Eatontown, NJ 07724
732-475-2186

Adult-Use Only

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Fort Lee

461-469 West St
Fort Lee, NJ 07024
973-200-7696

Adult-Use & Medical, Delivery Available

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Mister Jones

Little Falls

655 US 46 East
Little Falls, NJ 07424
973-638-2454

Adult-Use Only

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Rochelle Park

174 NJ-17 N
Rochelle Park, NJ 07662
973-370-3150

Adult-Use & Medical, Delivery Available

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Wharton

325 NJ-15
Wharton, NJ 07885
973-786-1810

Adult-Use & Medical, Delivery Available

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Carroll

3560 Dolson Ct NW B
Carroll, OH 43112
220-666-1690

Adult-Use & Medical

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Cincinnati

830 Reedy Street
Cincinnati, OH 45202
513-572-5696

Adult-Use & Medical

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Coshocton

23024 Co Road 621, Suite 1
Coshocton, OH 43812
740-295-9182

Adult-Use & Medical

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Englewood

7701 Hoke Road
Englewood, OH 45315
326-220-4185

Adult-Use & Medical

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Lewis Center

3812 E. Powell Road
Lewis Center, OH 43035

Adult-Use & Medical

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Piqua

1206-1208 Recker Road
Piqua, OH 45356
937-910-5832

Adult-Use & Medical

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Sandusky

6019 Milan Road
Sandusky, OH 44870
567-202-1985

Adult-Use & Medical

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Cranberry

20013 US-19
Cranberry Township, PA 16066
724-890-5342

Medical Only

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Monaca

1451 Old Brodhead Rd
Monaca, PA 15061
878-978-3097

Medical Only

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Scranton

605 Davis Street
Scranton, PA 18505
717-606-1268

Medical Only

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Wayne

745 W Lancaster Ave
Wayne, PA 19087
484-224-2766

Medical Only

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Whitehall

2030 MacArthur Rd
Whitehall, PA 18052
610-553-2037

Medical Only

NEW STORE ALERT: East Coasting now open in Eatontown, NJ.  More information.

What Are The Effects Of Cannabis?

6 minute read

Whether you are curious about cannabis for the first time or you have been using it for years, understanding what it actually does to your body and mind is important. Cannabis affects everyone a little differently, and with so many products and consumption methods available today, the experience can vary quite a bit depending on what you use and how you use it. 

How Cannabis Works In The Body

Cannabis contains hundreds of chemical compounds, but the two you will hear about most are THC (tetrahydrocannabinol) and CBD (cannabidiol). THC is the compound responsible for the psychoactive effects, meaning the feeling of being high. CBD, on the other hand, does not produce a high and is associated with more calming, therapeutic effects.

When you consume cannabis, these compounds interact with your body’s endocannabinoid system (ECS). The ECS is a network of receptors found throughout the brain and body that plays a role in regulating mood, memory, appetite, sleep, and pain. THC binds directly to receptors in this system, which is what triggers the range of effects people commonly associate with cannabis use.

The Short-Term Effects You Can Expect

The short-term effects of cannabis tend to set in within minutes if you are smoking or vaping, or anywhere from 30 minutes to two hours if you are consuming an edible. These effects can last between one and several hours depending on the dose and the individual.

Common short-term effects include:

  • Euphoria and relaxation: Many people report a sense of happiness, calm, or general well-being shortly after consuming cannabis. This is one of the most frequently cited reasons people use it recreationally.
  • Altered perception of time and sensory experience: Colors may appear more vivid, music may sound more engaging, and time can feel like it is passing more slowly than usual.
  • Increased appetite: Often referred to colloquially as the munchies, cannabis can significantly increase appetite, which is also why it has been used medically for patients dealing with appetite loss.
  • Dry mouth and red eyes: These are two of the most recognizable physical side effects and are caused by how THC interacts with glands and blood vessels.
  • Impaired short-term memory and concentration: Cannabis can make it harder to retain new information or stay focused during and shortly after use.
  • Increased heart rate: THC can temporarily raise the heart rate, which is worth noting for anyone with a heart condition or cardiovascular concerns.

How The Method Of Consumption Changes The Experience

One of the most important things to understand about cannabis effects is that the method of consumption has a significant impact on how quickly you feel those effects and how intense they are.

Smoking or vaping cannabis delivers THC to your bloodstream rapidly through the lungs, meaning the onset of effects is almost immediate. This makes it easier to gauge how you are feeling and adjust accordingly. Edibles work quite differently. Because they are processed through the digestive system, the effects take much longer to kick in, but they also tend to be more potent and longer lasting. Many first-time users make the mistake of taking more of an edible because they do not feel anything right away, only to find the full effect hits them much harder than expected. Tinctures and oils absorbed under the tongue fall somewhere in between, typically taking effect within 15 to 45 minutes.

Potential Therapeutic Benefits

Beyond recreational use, cannabis has a growing body of research behind its potential therapeutic applications. Many people turn to cannabis for help managing specific health concerns, and in 2026 the medical landscape around cannabis continues to evolve.

Some of the most well-researched potential benefits include:

  • Pain management: Cannabis, particularly CBD-rich products, has been studied for its ability to help manage chronic pain and inflammation.
  • Anxiety and stress relief: Lower doses of THC and higher doses of CBD are often associated with reduced anxiety and a calmer state of mind. Higher doses of THC, however, can have the opposite effect.
  • Improved sleep: Many users report that cannabis helps them fall asleep more easily and stay asleep longer, though research on long-term sleep quality is still ongoing.
  • Nausea reduction: Cannabis has long been used to help manage nausea, particularly in patients undergoing chemotherapy.
  • Appetite stimulation: As mentioned above, this effect has real clinical value for people dealing with conditions that suppress appetite.

It is worth noting that therapeutic outcomes vary from person to person, and cannabis is not a replacement for professional medical advice or treatment. Always speak with a healthcare provider before using cannabis for a medical purpose.

The Risks And Side Effects To Know About

Cannabis is not without its risks, and being informed about the less desirable effects is just as important as knowing the benefits. For some people, particularly those who are new to cannabis or who consume high doses, the experience can be uncomfortable.

Potential risks and negative effects include:

  • Anxiety and paranoia: High doses of THC can cause or worsen anxiety and paranoia, especially in people who are predisposed to these conditions.
  • Impaired coordination and reaction time: Cannabis affects motor skills and judgment, which is why driving under the influence is dangerous and illegal.
  • Dependence and withdrawal: While cannabis is not as addictive as many other substances, regular, heavy use can lead to cannabis use disorder, with withdrawal symptoms such as irritability, sleep disruption, and appetite changes when use is stopped.
  • Impact on developing brains: Research consistently shows that cannabis use during adolescence can negatively affect brain development, memory, and cognitive function. Cannabis is not recommended for anyone under the age of 21.
  • Respiratory effects: Smoking cannabis can irritate the lungs and airways over time, similar to other forms of smoking.

Factors That Influence Your Experience

No two people will have exactly the same experience with cannabis, even if they consume the same product in the same amount. Several personal and environmental factors play a role in shaping your experience.

These include your body weight and metabolism, your tolerance level based on prior use, the potency and strain of the product, your current mood and mental state, and even the setting in which you consume it. This is why starting low and going slow is the most commonly recommended approach, particularly for new users or those trying a new product.

Cannabis Strains And What They Mean

You have likely heard the terms indica, sativa, and hybrid when browsing cannabis products. Traditionally, indica strains have been associated with more relaxing, body-focused effects, while sativa strains are linked to more energizing, cerebral experiences. Hybrid strains aim to combine elements of both.

It is important to understand that these distinctions are a simplified way of categorizing cannabis and that the actual effects are largely determined by the specific chemical profile of the product, including its THC and CBD ratios and the presence of other compounds called terpenes. Terpenes contribute to the aroma and flavor of cannabis and are increasingly understood to play a role in shaping its effects.

Earn Rewards on Every Purchase With the Ascenders Club

Whether you are an experienced smoker or cannabis curious, every purchase at Ascend adds up to real savings. The Ascenders Club is Ascend’s free loyalty rewards program, where you earn 1 point for every $1 spent (pre-tax) at any participating location.

Points redeem for discounts at checkout, and they go even further on Ascend’s top brands, including Ozone, Simply Herb, Effin’, High Wired, Common Goods, and Royale, where your points are worth double.

Standard redemption:

  • 250 points = $5 off
  • 500 points = $10 off
  • 1,000 points = $20 off
  • 1,500 points = $30 off
  • 5,000 points = $100 off (Platinum and Legends members only)

Track your balance in the Ascend Dispensary app, available on the Apple App Store and Google Play, or through Ascend’s email communications. Points expire 90 days after your last point-earning transaction.

Join for free at any Ascend location or at letsascend.com/ascenders-club.

Ready To Explore Cannabis With Confidence?

Understanding the effects of cannabis puts you in the driver’s seat when it comes to making smart, safe choices. Whether you are looking to unwind after a long day, find relief from a chronic condition, or simply explore what cannabis has to offer, knowledge is your most valuable tool. At Ascend, the team is committed to helping you navigate your cannabis journey with clarity and confidence. Stop by, ask questions, and let the experts help you find the right product for your needs and goals. Your best experience with cannabis starts with being informed, and it starts here.

 By Ascend Wellness, Highnote Editor

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